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A Cryostat is a specialized freezing microtome used in histology and pathology laboratories for cutting thin sections of frozen tissue specimens. It employs a cryogenic cooling system to maintain tissue specimens at sub-zero temperatures, allowing for the production of frozen tissue sections without the need for fixation and embedding. Cryostats offer precise temperature control, motorized specimen advance mechanisms, and ergonomic designs for rapid and efficient sectioning. Key specifications include:

• Temperature range: Cooling capabilities to maintain specimen temperatures below freezing (e.g., -20°C to -30°C) for cryosectioning
• Section thickness range: Adjustable cutting settings typically ranging from 1 to 100 micrometers for fine control over section thickness
• Specimen orientation: Horizontal or vertical specimen orientation options to suit different cutting preferences and specimen types
• Cryoembedding: Compatibility with various freezing media and embedding techniques for optimal tissue preservation and sectioning
• Safety features: Safety interlocks, temperature alarms, and emergency stop mechanisms to ensure user safety during operation